Bone health in subjects with type 1 diabetes for more than 50 years.

ABSTRACT:

Aims

Few data regarding prevalence of and risk factors for poor bone health in aging individuals with long-standing T1D are available. In this study, we aim to describe the prevalence of bone fragility and to identify factors associated with low bone density in individuals with long-term T1D.

Methods

We examined the prevalence of non-vertebral fractures in 985 subjects enrolled in the Joslin 50-Year Medalist Study and measured bone mineral density (BMD) by dual-energy X-ray absorptiometry at the femoral neck, lumbar spine and radius in a subset (65 subjects, mean age 62.6 years, duration 52.5 years, HbA1c 7.1%) with no significant clinical or demographic differences from the rest of the cohort.

Results

Medalists have low prevalence of fractures (0.20% hip and 0.91% wr

SUBMITTER: Maddaloni E 

PROVIDER: S-EPMC5406751 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature