Psychological Factors May Play an Important Role in Pediatric Crohn's Disease Symptoms and Disability.

ABSTRACT:

Objective

To examine the relative contributions of disease activity and psychological factors to self-reported symptoms and disability in children with Crohn's disease.

Study design

Participants (n = 127 children age 8-18 years) completed questionnaires on symptom severity and disability, as well as psychological measures assessing anxiety, depression, pain beliefs and coping. Disease activity was measured by the Pediatric Crohn's Disease Activity Index. Structural equation modeling was used to test the effects of disease activity and psychological factors on symptoms and disability.

Results

In the hypothesized model predicting symptoms, psychological factors (β = 0.58; P < .001) were significantly associated with disease symptoms but disease activity was not. The mod

SUBMITTER: van Tilburg MAL 

PROVIDER: S-EPMC5407185 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature