Pathologic and Treatment Outcomes Among a Geriatric Population of Endometrial Cancer Patients: An NRG Oncology/Gynecologic Oncology Group Ancillary Data Analysis of LAP2.

ABSTRACT:

Objectives

Elderly endometrial cancer patients have worse disease-specific survival than their younger counterparts, but the cause for this discrepancy is unknown. The goal of this analysis is to compare outcomes by age in a fully staged elderly endometrial cancer population.

Methods/materials

This is an analysis of patients on Gynecologic Oncology Group Study (GOG) LAP2, which included clinically early stage endometrial cancer patients randomized to laparotomy versus laparoscopy for surgical staging. Patients were divided into risk groups based on criteria defined by GOG protocol 99. Differences in outcomes and adjuvant therapy were assessed within these risk groups.

Results

LAP2 included 715 patients 70 years or older. With increasing age, worse tumor characteristic

SUBMITTER: Bishop EA 

PROVIDER: S-EPMC5407305 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature