Early postnatal illness severity scores predict neurodevelopmental impairments at 10 years of age in children born extremely preterm.

ABSTRACT:

Objective

A neonatal illness severity score, The Score for Neonatal Acute Physiology-II (SNAP-II), predicts neurodevelopmental impairments at two years of age among children born extremely preterm. We sought to evaluate to what extent SNAP-II is predictive of cognitive and other neurodevelopmental impairments at 10 years of age.

Study design

In a cohort of 874 children born before 28 weeks of gestation, we prospectively collected clinical, physiologic and laboratory data to calculate SNAP-II for each infant. When the children were 10 years old, examiners who were unaware of the child's medical history assessed neurodevelopmental outcomes, including neurocognitive, gross motor, social and communication functions, diagnosis and treatment of seizures or attention deficit hypera

SUBMITTER: Logan JW 

PROVIDER: S-EPMC5407946 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature