Global Transmission Dynamics of Measles in the Measles Elimination Era.

ABSTRACT: Although there have been many epidemiological reports of the inter-country transmission of measles, systematic analysis of the global transmission dynamics of the measles virus (MV) is limited. In this study, we applied phylogeographic analysis to characterize the global transmission dynamics of the MV using large-scale genetic sequence data (obtained for 7456 sequences) from 115 countries between 1954 and 2015. These analyses reveal the spatial and temporal characteristics of global transmission of the virus, especially in Australia, China, India, Japan, the UK, and the USA in the period since 1990. The transmission is frequently observed, not only within the same region but also among distant and frequently visited areas. Frequencies of export from measles-endemic countries, such as Chin

SUBMITTER: Furuse Y 

PROVIDER: S-EPMC5408688 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature