First-trimester maternal protein intake and childhood kidney outcomes: the Generation R Study.

ABSTRACT:

Background

Nutritional exposures during in utero development may have long-lasting consequences for postnatal renal health. Animal studies suggest that specifically maternal dietary protein intake during pregnancy influences childhood kidney function.

Objective

We examined the associations of total, animal, and vegetable maternal protein intake during pregnancy with kidney volume and function in school-aged children.

Design

This study was conducted in 3650 pregnant women and their children who were participating in a population-based cohort study from early life onward. First-trimester energy-adjusted maternal protein intake was assessed with a food-frequency questionnaire. At the child's age of 6 y, we assessed kidney volume, estimated glomerular filtration rate (eGF

SUBMITTER: Miliku K 

PROVIDER: S-EPMC5408936 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature