Using conventional F-statistics to study unconventional sex-chromosome differentiation.

ABSTRACT: Species with undifferentiated sex chromosomes emerge as key organisms to understand the astonishing diversity of sex-determination systems. Whereas new genomic methods are widening opportunities to study these systems, the difficulty to separately characterize their X and Y homologous chromosomes poses limitations. Here we demonstrate that two simple F-statistics calculated from sex-linked genotypes, namely the genetic distance (F_st) between sexes and the inbreeding coefficient (F_is) in the heterogametic sex, can be used as reliable proxies to compare sex-chromosome differentiation between populations. We correlated these metrics using published microsatellite data from two frog species (Hyla arboreaand Rana temporaria), and show tha

SUBMITTER: Rodrigues N 

PROVIDER: S-EPMC5410149 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature