Node Identification Using Inter-Regional Correlation Analysis for Mapping Detailed Connections in Resting State Networks.

ABSTRACT: Brain function is often characterized by the connections and interactions between highly interconnected brain regions. Pathological disruptions in these networks often result in brain dysfunction, which manifests as brain disease. Typical analysis investigates disruptions in network connectivity based correlations between large brain regions. To obtain a more detailed description of disruptions in network connectivity, we propose a new method where functional nodes are identified in each region based on their maximum connectivity to another brain region in a given network. Since this method provides a unique approach to identifying functionally relevant nodes in a given network, we can provide a more detailed map of brain connectivity and determine new measures of network connectivity. We

SUBMITTER: Sohn WS 

PROVIDER: S-EPMC5410606 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature