Maternal vitamin D concentrations during pregnancy, fetal growth patterns, and risks of adverse birth outcomes.

ABSTRACT:

Background

Maternal vitamin D deficiency during pregnancy may affect fetal outcomes.

Objective

The objective of this study was to examine whether maternal 25-hydroxyvitamin D [25(OH)D] concentrations in pregnancy affect fetal growth patterns and birth outcomes.

Design

This was a population-based prospective cohort in Rotterdam, Netherlands in 7098 mothers and their offspring. We measured 25(OH)D concentrations at a median gestational age of 20.3 wk (range: 18.5-23.3 wk). Vitamin D concentrations were analyzed continuously and in quartiles. Fetal head circumference and body length and weight were estimated by repeated ultrasounds, and preterm birth (gestational age <37 wk) and small size for gestational age (less than the fifth percentile) were determined.

Results</

SUBMITTER: Miliku K 

PROVIDER: S-EPMC5410992 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature