Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Portugal.

ABSTRACT:

Objective

Although the incidence of meningococcal disease has been declining over the past decade in Portugal MenB meningococci is still an important cause of meningitis and sepsis. The aim of this study was to estimate the strain coverage of the 4CMenB vaccine in Portugal in order to support health policies for prevention and control of meningococcal disease.

Methods

Since 2002 the clinical and laboratory notification of meningococcal disease is mandatory in Portugal. National database includes since then all confirmed cases notified to the reference laboratory or to the Directorate of Health. Strains included in this study were all the invasive MenB isolated from the 1st July 2011 to the 30th June 2015, sent to the reference laboratory. To predict the vaccine strain covera

SUBMITTER: Simoes MJ 

PROVIDER: S-EPMC5411059 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature