Actin filament assembly by bacterial factors VopL/F: Which end is up?

ABSTRACT: Competing models have been proposed for actin filament nucleation by the bacterial proteins VopL/F. In this issue, Burke et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201608104) use direct observation to demonstrate that VopL/F bind the barbed and pointed ends of actin filaments but only nucleate new filaments from the pointed end.

SUBMITTER: Vizcarra CL 

PROVIDER: S-EPMC5412575 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature