Maternal vascular malperfusion of the placental bed associated with hypertensive disorders in the Boston Birth Cohort.

ABSTRACT:

Introduction

The associations of maternal conditions, before or during pregnancy, with placental lesions have not been adequately studied in populations.

Methods

In the Boston Birth Cohort, we evaluated associations between three maternal medical conditions (hypertensive disorders [HDs], gestational/pre-gestational diabetes and obesity), and placental histological findings, using a standardized classification system proposed by the Amsterdam Placental Workshop Group. Placental pathology diagnoses and clinical data from 3074 mothers with clinical indications who delivered singleton live births at the Boston Medical Center between October 1998 and November 2013 were evaluated. Associations between each maternal condition and maternal vascular malperfusion (MVM) of the placenta

SUBMITTER: Bustamante Helfrich B 

PROVIDER: S-EPMC5412713 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature