Development of a repository of individual participant data from randomized controlled trials of therapists delivered interventions for low back pain.

ABSTRACT:

Background

Individual patient data (IPD) meta-analysis of existing randomized controlled trials (RCTs) is a promising approach to achieving sufficient statistical power to identify sub-groups. We created a repository of IPD from multiple low back pain (LBP) RCTs to facilitate a study of treatment moderators. Due to sparse heterogeneous data, the repository needed to be robust and flexible to accommodate millions of data points prior to any subsequent analysis.

Methods

We systematically identified RCTs of therapist delivered intervention for inclusion to the repository. Some were obtained through project publicity. We requested both individual items and aggregate scores of all baseline characteristics and outcomes for all available time points. The repository is made up of a

SUBMITTER: Hee SW 

PROVIDER: S-EPMC5412919 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature