Ontology highlight
ABSTRACT:
SUBMITTER: Yunusova AM
PROVIDER: S-EPMC5413903 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Yunusova Anastasia M AM Fishman Veniamin S VS Vasiliev Gennady V GV Battulin Nariman R NR
Open biology 20170401 4
Factor-mediated reprogramming of somatic cells towards pluripotency is a low-efficiency process during which only small subsets of cells are successfully reprogrammed. Previous analyses of the determinants of the reprogramming potential are based on average measurements across a large population of cells or on monitoring a relatively small number of single cells with live imaging. Here, we applied lentiviral genetic barcoding, a powerful tool enabling the identification of familiar relationships ...[more]