Epistatic and allelic interactions control expression of ribosomal RNA gene clusters in Arabidopsis thaliana.

ABSTRACT:

Background

Ribosomal RNA (rRNA) accounts for the majority of the RNA in eukaryotic cells, and is encoded by hundreds to thousands of nearly identical gene copies, only a subset of which are active at any given time. In Arabidopsis thaliana, 45S rRNA genes are found in two large ribosomal DNA (rDNA) clusters and little is known about the contribution of each to the overall transcription pattern in the species.

Results

By taking advantage of genome sequencing data from the 1001 Genomes Consortium, we characterize rRNA gene sequence variation within and among accessions. Notably, variation is not restricted to the pre-rRNA sequences removed during processing, but it is also present within the highly conserved ribosomal subunits. Through linkage mapping we assign these variants

SUBMITTER: Rabanal FA 

PROVIDER: S-EPMC5414317 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature