Bimatoprost 0.03% for the Treatment of Eyebrow Hypotrichosis.

ABSTRACT:

Background

Eyebrow loss may have substantial negative functional and social consequences.

Objective

Evaluate the safety and efficacy of bimatoprost 0.03% in subjects with eyebrow hypotrichosis.

Methods

This multicenter, double-masked study randomized adult females or males with eyebrow hypotrichosis to receive bimatoprost 0.03% twice (BID) or once daily (QD) or vehicle BID for 7 months. Primary endpoint was overall eyebrow fullness at Month 7. Secondary endpoints included eyebrow fullness (mm), darkness (intensity units), and subject satisfaction with treatment. Safety was also assessed.

Results

At Month 7, the proportion of subjects with improvement was significantly higher in bimatoprost groups versus vehicle (both, p < .001). Improvements occurred in both bi

SUBMITTER: Carruthers J 

PROVIDER: S-EPMC5414776 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature