Low potential for mechanical transmission of Ebola virus via house flies (Musca domestica).

ABSTRACT:

Background

Ebola virus (EBOV) infection results in high morbidity and mortality and is primarily transmitted in communities by contact with infectious bodily fluids. While clinical and experimental evidence indicates that EBOV is transmitted via mucosal exposure, the ability of non-biting muscid flies to mechanically transmit EBOV following exposure to the face had not been assessed.

Results

To investigate this transmission route, house flies (Musca domestica Linnaeus) were used to deliver an EBOV/blood mixture to the ocular/nasal/oral facial mucosa of four cynomolgus macaques (Macaca fascicularis Raffles). Following exposure, macaques were monitored for evidence of infection through the conclusion of the study, days 57 and 58. We found no evidence of systemic infection in a

SUBMITTER: Haddow AD 

PROVIDER: S-EPMC5415731 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature