Severe Pneumocystis jirovecii pneumonia in an idiopathic CD4⁺ lymphocytopenia patient: case report and review of the literature.

ABSTRACT:

Introduction

When diagnosing Pneumocystis jirovecii pneumonia (PJP), the clinical suspicion must be confirmed by laboratory tests. PJP is rarely described in patients with idiopathic CD4⁺ lymphocytopenia (ICL), a rare T-cell deficiency of unknown origin with persistently low levels of CD4⁺ T-cells (<300 µl^-1 or <20 % of total lymphocytes) but repeated negative human immunodeficiency virus (HIV) tests. We retrospectively analysed a case of an ICL patient with severe PJP associated with multiple opportunistic infections (OIs). We also reviewed the literature since 1986.

Case presentation

A laboratory-confirmed case of PJP associated with invasive candidiasis and cytomegalovirus infection was reported in an ICL patient. Despite early trea

SUBMITTER: Chumpitazi BFF 

PROVIDER: S-EPMC5415924 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature