Abdominal symptoms in cystic fibrosis and their relation to genotype, history, clinical and laboratory findings.

ABSTRACT:

Background & aims

Abdominal symptoms (AS) are a hallmark of the multiorgan-disease cystic fibrosis (CF). However, the abdominal involvement in CF is insufficiently understood and, compared to the pulmonary manifestation, still receives little scientific attention. Aims were to assess and quantify AS and to relate them to laboratory parameters, clinical findings, and medical history.

Methods

A total of 131 patients with CF of all ages were assessed with a new CF-specific questionnaire (JenAbdomen-CF score 1.0) on abdominal pain and non-pain symptoms, disorders of appetite, eating, and bowel movements as well as symptom-related quality of life. Results were metrically dimensioned and related to abdominal manifestations, history of surgery, P. aeruginosa and S. aureus colonizat

SUBMITTER: Tabori H 

PROVIDER: S-EPMC5417419 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature