The highly buffered Arabidopsis immune signaling network conceals the functions of its components.

ABSTRACT: Plant immunity protects plants from numerous potentially pathogenic microbes. The biological network that controls plant inducible immunity must function effectively even when network components are targeted and disabled by pathogen effectors. Network buffering could confer this resilience by allowing different parts of the network to compensate for loss of one another's functions. Networks rich in buffering rely on interactions within the network, but these mechanisms are difficult to study by simple genetic means. Through a network reconstitution strategy, in which we disassemble and stepwise reassemble the plant immune network that mediates Pattern-Triggered-Immunity, we have resolved systems-level regulatory mechanisms underlying the Arabidopsis transcriptome response to the immune sti

SUBMITTER: Hillmer RA 

PROVIDER: S-EPMC5417422 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature