A novel finite element model of the ovine lumbar intervertebral disc with anisotropic hyperelastic material properties.

ABSTRACT: The Ovine spine is an accepted model to investigate the biomechanical behaviour of the human lumbar one. Indeed, the use of animal models for in vitro studies is necessary to investigate the mechanical behaviour of biological tissue, but needs to be reduced for ethical and social reasons. The aim of this study was to create a finite element model of the lumbar intervertebral disc of the sheep that may help to refine the understanding of parallel in vitro experiments and that can be used to predict when mechanical failure occurs. Anisotropic hyperelastic material properties were assigned to the annulus fibrosus and factorial optimization analyses were performed to find out the optimal parameters of the ground substance and of the collagen fibers. For the ground substance of the annulus fibr

SUBMITTER: Casaroli G 

PROVIDER: S-EPMC5417645 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature