Sleep and survival among women with breast cancer: 30 years of follow-up within the Nurses' Health Study.

ABSTRACT:

Background

Breast cancer is a leading cause of cancer death in women. Sleep has been linked with mortality among cancer-free population; however, its association with survival among women with breast cancer is understudied.

Methods

Breast cancer patients (N=3682) reported their average sleep duration post diagnosis. Subsamples also provided their pre-diagnosis sleep duration (n=1949) and post-diagnosis sleep difficulties (n=1353). Multivariate Cox models estimated hazard ratios (HR) and confidence intervals (CI) of all-cause, breast cancer, and non-breast cancer mortality.

Results

At diagnosis, the mean age was 64.9 years and 91.7% were stage I or II. Women sleeping ⩾9 h per night post diagnosis had a strong higher risk of all-cause (multivariate HRs: MV-HR=1.37, CI=1

SUBMITTER: Trudel-Fitzgerald C 

PROVIDER: S-EPMC5418457 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature