The role of necroptosis in atherosclerotic disease.
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ABSTRACT:
SUBMITTER: Leeper NJ
PROVIDER: S-EPMC5419689 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
The role of necroptosis in atherosclerotic disease.
JACC. Basic to translational science 20161001 6
It is now known that cells don't always die by apoptosis, but can also undergo a process known as programmed cell necrosis, or necroptosis. In a study recently published in <i>Science Advances</i>, investigators reported that this pro-inflammatory process is active in human atherosclerosis, may promote growth of the necrotic core, and may serve as a novel molecular imaging and translational therapeutic target. These findings represent a major step in our goal to reduce coronary disease and strok ...[more]
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