Anemia risk in relation to lead exposure in lead-related manufacturing.

ABSTRACT:

Background

Lead-exposed workers may suffer adverse health effects under the currently regulated blood lead (BPb) levels. However, a probabilistic assessment about lead exposure-associated anemia risk is lacking. The goal of this study was to examine the association between lead exposure and anemia risk among factory workers in Taiwan.

Methods

We first collated BPb and indicators of hematopoietic function data via health examination records that included 533 male and 218 female lead-exposed workers between 2012 and 2014. We used benchmark dose (BMD) modeling to estimate the critical effect doses for detection of abnormal indicators. A risk-based probabilistic model was used to characterize the potential hazard of lead poisoning for job-specific workers by hazard index (HI). W

SUBMITTER: Hsieh NH 

PROVIDER: S-EPMC5420139 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature