Neuroleptics in the management of delirium in patients with advanced cancer.

ABSTRACT:

Purpose of review

Delirium is the most common and distressing neuropsychiatric syndrome in cancer patients. Few evidence-based treatment options are available due to the paucity of high quality of studies. In this review, we shall examine the literature on the use of neuroleptics to treat delirium in patients with advanced cancer. Specifically, we will discuss the randomized controlled trials that examined neuroleptics in the front line setting, and studies that explore second-line options for patients with persistent agitation.

Recent findings

Contemporary management of delirium includes identification and management of any potentially reversible causes, coupled with nonpharmacological approaches. For patients who do not respond adequately to these measures, pharmacologic m

SUBMITTER: Hui D 

PROVIDER: S-EPMC5420193 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature