Translation of rod-like template sequences into homochiral assemblies of stacked helical oligomers.

ABSTRACT: At the molecular level, translation refers to the production of a new entity according to a template that has a different chemical composition. In this way, chemical information may be translated from one molecule to another. The process is useful to synthesize structures and thus functions that might be difficult to create otherwise, and it reaches exquisite levels of efficiency in biological systems, as illustrated by protein expression from mRNA templates or by the assembly of the tobacco mosaic virus capsid protein according to the length of its RNA. In synthetic systems, examples of template-directed syntheses are numerous, but general and versatile schemes in which a non-natural sequence actually encodes the information necessary to produce a different sequence are few and far from b

SUBMITTER: Gan Q 

PROVIDER: S-EPMC5420310 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature