Maternal buprenorphine treatment and fetal neurobehavioral development.

ABSTRACT:

Background

Gestational opioid use/misuse is escalating in the United States; however, little is understood about the fetal effects of medications used to treat maternal opioid use disorders.

Objective

The purpose of this study was to determine the effect of maternal buprenorphine administration on longitudinal fetal neurobehavioral development.

Study design

Forty-nine buprenorphine-maintained women who attended a substance use disorder treatment facility with generally uncomplicated pregnancies underwent fetal monitoring for 60 minutes at times of trough and peak maternal buprenorphine levels. Data were collected at 24, 28, 32, and 36 weeks gestation. Fetal neurobehavioral indicators (ie, heart rate, motor activity, and their integration [fetal movement-fetal heart ra

SUBMITTER: Jansson LM 

PROVIDER: S-EPMC5420468 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature