Association between ABO and Rh Blood Groups and Risk of Preeclampsia: A Case-Control Study from Iran.

ABSTRACT:

Aim

Preeclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality. There is a genetic component in the development of PE with estimated heritability around 0.47. Several studies have investigated the association between maternal ABO blood groups (OMIM 110300) and risk of PE, with contradictory results have emerged. Considering that there is no study in this filed from Iranian population, the present case-control study was carried out at Shiraz (south-west Iran).

Material and methods

In this study 331 women; 121 pregnant with PE and 210 normotensive pregnant women were included. Using blood group O (for ABO blood groups) or Rh+ (for Rh blood groups) as a reference, odds ratios (ORs) and its 95% confidence intervals (95% CI) of PE risk were estimated from

SUBMITTER: Aghasadeghi F 

PROVIDER: S-EPMC5420769 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature