Neural activations are related to body-shape, anxiety, and outcomes in adolescent anorexia nervosa.

ABSTRACT: Anorexia nervosa (AN) is an illness that frequently begins during adolescence and involves weight loss. Two groups of adolescent girls (AN-A, weight-recovered following AN) and (HC-A, healthy comparison) completed a functional magnetic resonance imaging task involving social evaluations, allowing comparison of neural activations during self-evaluations, friend-evaluations, and perspective-taking self-evaluations. Although the two groups were not different in their whole-brain activations, anxiety and body shape concerns were correlated with neural activity in a priori regions of interest. A cluster in medial prefrontal cortex and the dorsal anterior cingulate correlated with the body shape questionnaire; subjects with more body shape concerns used this area less during self than friend eva

SUBMITTER: Xu J 

PROVIDER: S-EPMC5421407 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature