Association between concurrent use of prescription opioids and benzodiazepines and overdose: retrospective analysis.

ABSTRACT: Objectives To identify trends in concurrent use of a benzodiazepine and an opioid and to identify the impact of these trends on admissions to hospital and emergency room visits for opioid overdose.Design Retrospective analysis of claims data, 2001-13.Setting Administrative health claims database.Participants 315 428 privately insured people aged 18-64 who were continuously enrolled in a health plan with medical and pharmacy benefits during the study period and who also filled at least one prescription for an opioid.Interventions Concurrent benzodiazepine/opioid use, defined as an overlap of at least one day in the time periods covered by prescriptions for each drug. Main outcome measures Annual percentage of opioid users with concurrent benzodiazep

SUBMITTER: Sun EC 

PROVIDER: S-EPMC5421443 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature