Atosiban versus fenoterol as a uterine relaxant for external cephalic version: randomised controlled trial.

ABSTRACT:

Objective

 To compare the effectiveness of the oxytocin receptor antagonist atosiban with the beta mimetic fenoterol as uterine relaxants in women undergoing external cephalic version (ECV) for breech presentation.

Design

 Multicentre, open label, randomised controlled trial.

Setting

 Eight hospitals in the Netherlands, August 2009 to May 2014.

Participants

 830 women with a singleton fetus in breech presentation and a gestational age of more than 34 weeks were randomly allocated in a 1:1 ratio to either 6.75 mg atosiban (n=416) or 40 μg fenoterol (n=414) intravenously for uterine relaxation before ECV.

Main outcome measures

 The primary outcome measures were a fetus in cephalic position 30 minutes after the procedure and cephalic presentation at deliver

SUBMITTER: Velzel J 

PROVIDER: S-EPMC5421458 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature