"Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases.

ABSTRACT: The integration of different sources of biological information about what defines a behavioral phenotype is difficult to unify in an entity that reflects the arithmetic sum of its individual parts. In this sense, the challenge of Systems Biology for understanding the "psychiatric phenotype" is to provide an improved vision of the shape of the phenotype as it is visualized by "Gestalt" psychology, whose fundamental axiom is that the observed phenotype (behavior or mental disorder) will be the result of the integrative composition of every part. Therefore, we propose the term "Gestaltomics" as a term from Systems Biology to integrate data coming from different sources of information (such as the genome, transcriptome, proteome, epigenome, metabolome, phenome, and microbiome). In addition to

SUBMITTER: Gutierrez Najera NA 

PROVIDER: S-EPMC5422874 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature