Impact of 8-week linoleic acid intake in soy oil on Lp-PLA₂ activity in healthy adults.

ABSTRACT:

Background

No intervention follow-up study has examined the association between plasma n-6 polyunsaturated fatty acids (PUFAs) and lipoprotein-associated phospholipase A₂ (Lp-PLA₂), which is a risk factor for cardiovascular disease (CVD). We aimed to determine whether the administration of linoleic acid (LA, 18:2n-6) in soy oil affected Lp-PLA₂ activity in healthy adults.

Methods

Self-reported healthy participants (n = 150) were randomly assigned to three groups: a low LA group, in which 10 mL soy oil was replaced with one apple; a medium LA group, in which the typical food intake was maintained; and a high LA group, in which 1/3 cup of cooked refined rice was replaced with 9.9 g of soy oil capsules daily. Plasma fatty acids and Lp-PLA

SUBMITTER: Kim M 

PROVIDER: S-EPMC5422895 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature