Boosting LPMO-driven lignocellulose degradation by polyphenol oxidase-activated lignin building blocks.

ABSTRACT:

Background

Many fungi boost the deconstruction of lignocellulosic plant biomass via oxidation using lytic polysaccharide monooxygenases (LPMOs). The application of LPMOs is expected to contribute to ecologically friendly conversion of biomass into fuels and chemicals. Moreover, applications of LPMO-modified cellulose-based products may be envisaged within the food or material industry.

Results

Here, we show an up to 75-fold improvement in LPMO-driven cellulose degradation using polyphenol oxidase-activated lignin building blocks. This concerted enzymatic process involves the initial conversion of monophenols into diphenols by the polyphenol oxidase MtPPO7 from Myceliophthora thermophila C1 and the subsequent oxidation of cellulose by MtLPMO9B. Interestin

SUBMITTER: Frommhagen M 

PROVIDER: S-EPMC5424327 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature