Comparative Genomics of Host-Symbiont and Free-Living Oceanobacillus Species.

ABSTRACT: Survival in a given environment requires specific functions, so genomic variation is anticipated within in individual taxonomic groups that exhibit a large diversity in lifestyles. In this study, we sequence and assemble the genome of Oceanobacillus faecalis strain HM6, a resident of the human gut. Using the genus Oceanobacillus and the HM6 draft genome sequence, we explore the functional requirements for survival in a symbiotic arrangement within the human gut, in contrast to free living in the environment. Comparative genomics of seven available Oceanobacillus complete genomes highlight a genomically heterogeneous group. Our analysis did not find strict phylogenetic separation between free-living and host-symbiont Oceanobacillus members. By comparing functional gene content between host-

SUBMITTER: Kumar Mondal A 

PROVIDER: S-EPMC5425236 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature