The impact of large structural brain changes in chronic stroke patients on the electric field caused by transcranial brain stimulation.

ABSTRACT: Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (TDCS) are two types of non-invasive transcranial brain stimulation (TBS). They are useful tools for stroke research and may be potential adjunct therapies for functional recovery. However, stroke often causes large cerebral lesions, which are commonly accompanied by a secondary enlargement of the ventricles and atrophy. These structural alterations substantially change the conductivity distribution inside the head, which may have potentially important consequences for both brain stimulation methods. We therefore aimed to characterize the impact of these changes on the spatial distribution of the electric field generated by both TBS methods. In addition to confirming the safety of TBS in the presence of lar

SUBMITTER: Minjoli S 

PROVIDER: S-EPMC5426045 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature