Longitudinal associations between late-life depression dimensions and cognitive functioning: a cross-domain latent growth curve analysis.

ABSTRACT:

Background

Cognitive impairment and depression often co-occur in older adults, but it is not clear whether depression is a risk factor for cognitive decline, a psychological reaction to cognitive decline, or whether changes in depressive symptoms correlate with changes in cognitive performance over time. The co-morbid manifestation of depression and cognitive impairment may reflect either a causal effect or a common cause, depending on the specific symptoms experienced and the cognitive functions affected.

Method

The study sample comprised 1506 community-dwelling older adults aged ⩾65 years from the Longitudinal Aging Study Amsterdam (LASA). We conducted cross-domain latent growth curve analyses to examine longitudinal associations between late-life depression dimensions (i.

SUBMITTER: Brailean A 

PROVIDER: S-EPMC5426346 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature