Template-directed synthesis of linear porphyrin oligomers: classical, Vernier and mutual Vernier.

ABSTRACT: Three different types of template-directed syntheses of linear porphyrin oligomers are presented. In the classical approach the product has the same number of binding sites as the template, whereas in Vernier reactions the product has the lowest common multiple of the numbers of binding sites in the template and the building block. Mutual Vernier templating is like Vernier templating except that both strands of the Vernier complex undergo coupling simultaneously, so that it becomes impossible to say which is the 'template' and which is the 'building block'. The template-directed synthesis of monodisperse linear oligomers is more difficult than that of cyclic oligomers, because the products of linear templating have reactive ends. All three types of templating are demonstrated here, and use

SUBMITTER: Kamonsutthipaijit N 

PROVIDER: S-EPMC5426366 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature