HIV infection as vascular risk: A systematic review of the literature and meta-analysis.

ABSTRACT:

Importance

The vascular risk attributable to HIV infection is rising. The heterogeneity of the samples studied is an obstacle to understanding whether HIV is a vascular risk across geographic regions.

Objective

To test the hypothesis that HIV infection is a vascular risk factor, and that the risk conferred by HIV varies by geographical region.

Data sources

A systematic search of publications was carried out in seven electronic databases: PubMed, The Cochrane Library, EMBASE, Web of Science, LILACS, ClinicalTrials.gov, and WHO International Clinical Trials Registry Platform from inception to July 2015.

Study selection

We included longitudinal studies of HIV+ individuals and their risk of vascular outcomes of ≥ 50 HIV+ cases and excluded studies on biomarkers of

SUBMITTER: Gutierrez J 

PROVIDER: S-EPMC5426615 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature