Epidemiology of Mixed Connective Tissue Disease, 1985-2014: A Population-Based Study.

ABSTRACT:

Objective

To characterize the epidemiology of mixed connective tissue disease (MCTD) from 1983 to 2014.

Methods

An inception cohort of patients with incident MCTD in 1985-2014 in Olmsted County, Minnesota was identified based on comprehensive individual medical record review. Diagnosis of MCTD required fulfillment of at least 1 of the 4 widely accepted diagnostic criteria without fulfillment of classification criteria for other connective tissue diseases. Data were collected on demographic characteristics, clinical presentation, laboratory investigations, and mortality.

Results

A total of 50 incident cases of MCTD were identified (mean age 48.1 years and 84% were female). The annual incidence of MCTD was 1.9 per 100,000 population. Raynaud's phenomenon was the most co

SUBMITTER: Ungprasert P 

PROVIDER: S-EPMC5426802 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature