Cytoreductive nephrectomy in the modern era: Predictors of use, morbidity, and survival.

ABSTRACT:

Introduction

To determine tumour, patient, and provider factors associated with cytoreductive nephrectomy (CN) use and to identify those factors that predicted short-term and long-term surgical outcomes.

Methods

We performed a retrospective review (1998-2011) of the National Cancer Database, a U.S. population-based oncology outcomes database. The review included 36 549 patients with metastatic renal cell carcinoma (mRCC). We assessed predictors of CN use, length of stay (LOS), 30-day readmission, and 30-day mortality using multivariable logistic regression. The Cox proportional hazards model assessed predictors of overall survival (OS).

Results

Overall, 10 809 (29.6%) patients received CN, increasing from 15.2% to 36.1% over time. Private insurance (odds ratio [OR] 1.

SUBMITTER: Minnillo BJ 

PROVIDER: S-EPMC5426939 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature