Cattle genome-wide analysis reveals genetic signatures in trypanotolerant N'Dama.

ABSTRACT:

Background

Indigenous cattle in Africa have adapted to various local environments to acquire superior phenotypes that enhance their survival under harsh conditions. While many studies investigated the adaptation of overall African cattle, genetic characteristics of each breed have been poorly studied.

Results

We performed the comparative genome-wide analysis to assess evidence for subspeciation within species at the genetic level in trypanotolerant N'Dama cattle. We analysed genetic variation patterns in N'Dama from the genomes of 101 cattle breeds including 48 samples of five indigenous African cattle breeds and 53 samples of various commercial breeds. Analysis of SNP variances between cattle breeds using wMI, XP-CLR, and XP-EHH detected genes containing N'Dama-specific gen

SUBMITTER: Kim SJ 

PROVIDER: S-EPMC5427609 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature