Survival Benefit of Lung Transplantation in the Modern Era of Lung Allocation.

ABSTRACT:

Rationale

Lung transplantation is an accepted and increasingly employed treatment for advanced lung diseases, but the anticipated survival benefit of lung transplantation is poorly understood.

Objectives

To determine whether and for which patients lung transplantation confers a survival benefit in the modern era of U.S. lung allocation.

Methods

Data on 13,040 adults listed for lung transplantation between May 2005 and September 2011 were obtained from the United Network for Organ Sharing. A structural nested accelerated failure time model was used to model the survival benefit of lung transplantation over time. The effects of patient, donor, and transplant center characteristics on the relative survival benefit of transplantation were examined.

Measurements and mai

SUBMITTER: Vock DM 

PROVIDER: S-EPMC5427730 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature