Modeling Nosocomial Infections of Methicillin-Resistant Staphylococcus aureus with Environment Contamination^.

ABSTRACT: In this work, we investigate the role of environmental contamination on the clinical epidemiology of antibiotic-resistant bacteria in hospitals. Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that causes infections in different parts of the body. It is tougher to treat than most strains of Staphylococcus aureus or staph, because it is resistant to some commonly used antibiotics. Both deterministic and stochastic models are constructed to describe the transmission characteristics of MRSA in hospital setting. The deterministic epidemic model includes five compartments: colonized and uncolonized patients, contaminated and uncontaminated health care workers (HCWs), and bacterial load in environment. The basic reproduction number R ₀ is calculated, and its numerica

SUBMITTER: Wang L 

PROVIDER: S-EPMC5428062 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature