Posterior cingulate cross-hemispheric functional connectivity predicts the level of consciousness in traumatic brain injury.

ABSTRACT: Previous studies have demonstrated that altered states of consciousness are related to changes in resting state activity in the default-mode network (DMN). Anatomically, the DMN can be divided into anterior and posterior regions. The anterior DMN includes the perigenual anterior cingulate cortex and other medial prefrontal cortical regions, whereas the posterior DMN includes regions such as the posterior cingulate cortex (PCC) and the temporal parietal junction (TPJ). Although differential roles have been attributed to the anterior and posterior DMN regions, their exact contributions to consciousness levels remain unclear. To investigate the specific role of the posterior DMN in consciousness levels, we investigated 20 healthy controls (7 females, mean age = 33.6 years old) and 20 traumati

SUBMITTER: Zhang H 

PROVIDER: S-EPMC5428308 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature