Unscreened older men diagnosed with prostate cancer are at increased risk of aggressive disease.

ABSTRACT:

Background

To evaluate the relationship between PSA testing history and high-risk disease among older men diagnosed with prostate cancer.

Methods

Records from 1993 to 2014 were reviewed for men who underwent radiotherapy for prostate cancer at age 75 years or older. Patients were classified into one of four groups based on PSA-testing history: (1) no PSA testing; (2) incomplete/ineffective PSA testing; (3) PSA testing; or (4) cannot be determined. Outcomes of interest were National Comprehensive Cancer Network (NCCN) risk group (that is, low, intermediate or high risk) and biopsy grade at diagnosis. Multivariable logistic regression was used to determine the association between PSA testing history and high-risk cancer.

Results

PSA-testing history was available in 274

SUBMITTER: Tosoian JJ 

PROVIDER: S-EPMC5429182 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature