Sellar and clival plasmacytomas: case series of 5 patients with systematic review of 65 published cases.

ABSTRACT:

Purpose

Parasellar plasmacytomas are rare tumors localized to the sellar region arising from plasma cells. Knowledge of clinical, imaging, surgical, and pathological characteristics is limited to single case reports.

Methods

A retrospective analysis of five primary cases was conducted, followed by systematic review of English language articles using PubMed in accordance with PRISMA guidelines.

Results

Five primary case patients include four men and one woman, ages 60-77, followed up to 3 years. A systematic review identified 65 additional patients, of whom 65% presented with cranial nerve palsies and 15% with hypopituitarism. Sixteen percent had history of known multiple myeloma (MM) while 37% were diagnosed concurrently with MM on presentation of parasellar plasmacyt

SUBMITTER: Lee J 

PROVIDER: S-EPMC5429193 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature