High Prevalence of Thyroid Disease and Role of Salivary Gland Scintigraphy in Patients with Xerostomia.

ABSTRACT:

Purpose

Although Sjögren's syndrome (SS) is the most common disease causing xerostomia, autoimmune thyroid diseases can also affect the salivary glands. The aim of our study was to estimate the prevalence of thyroid diseases (TD) in subjects with symptoms of xerostomia and evaluate the efficacy of salivary gland scintigraphy (SGS) in the detection of TD in patients with SS and without SS.

Methods

We retrospectively reviewed the SGS findings of 173 subjects (men:women, 29:144) with symptoms of xerostomia. Ejection fractions (EF) in the parotid and submandibular glands were calculated. Thyroid disease was diagnosed on the basis of the results of the visual assessment of tracer uptake in the thyroid gland on SGS images as well as serological thyroid function tests.

Results</

SUBMITTER: Jung JH 

PROVIDER: S-EPMC5429303 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature