Laser thermal ablation for mesiotemporal epilepsy: Analysis of ablation volumes and trajectories.

ABSTRACT:

Objective

To identify features of ablations and trajectories that correlate with optimal seizure control and minimize the risk of neurocognitive deficits in patients undergoing laser interstitial thermal therapy (LiTT) for mesiotemporal epilepsy (mTLE).

Methods

Clinical and radiographic data were reviewed from a prospectively maintained database of all patients undergoing LiTT for the treatment of mTLE at the University of Miami Hospital. Standard preoperative and postoperative evaluations, including contrast-enhanced magnetic resonance imaging (MRI) and neuropsychological testing, were performed in all patients. Laser trajectory and ablation volumes were computed both by manual tracing of mesiotemporal structures and by nonrigid registration of ablation cavities to a common

SUBMITTER: Jermakowicz WJ 

PROVIDER: S-EPMC5429877 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature