Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study.

ABSTRACT: Objective To determine the role of early onset versus late onset hypertension as a risk factor for hypertension in offspring and cardiovascular death.Design Multigenerational, prospective cohort study.Setting Framingham Heart Study.Participants Two generations of community dwelling participants with blood pressure measurements performed at serial examinations spanning six decades: 3614 first generation participants with mortality data and 1635 initially non-hypertensive second generation participants with data available on parental blood pressure.Main outcome measures The main outcome measures were relation of parental early onset hypertension (age <55 years) with incidence of hypertension in offspring, using regression analyses, and relation of age at hy

SUBMITTER: Niiranen TJ 

PROVIDER: S-EPMC5430541 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature